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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SAMHD1
All Species:
7.58
Human Site:
S102
Identified Species:
13.89
UniProt:
Q9Y3Z3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y3Z3
NP_056289.2
626
72201
S102
G
E
R
K
K
L
L
S
Y
I
Q
R
L
V
Q
Chimpanzee
Pan troglodytes
XP_514624
382
43769
Rhesus Macaque
Macaca mulatta
XP_001097562
728
83194
S204
G
E
R
K
K
L
L
S
Y
I
Q
R
S
G
Q
Dog
Lupus familis
XP_542986
665
76981
A140
G
D
R
K
K
L
Q
A
C
I
Q
Q
L
S
E
Cat
Felis silvestris
Mouse
Mus musculus
Q60710
627
72632
E103
E
E
R
K
K
M
I
E
C
I
Q
Q
L
S
Q
Rat
Rattus norvegicus
XP_230789
677
77635
E158
E
Q
R
K
K
M
I
E
C
I
Q
K
L
N
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZJL9
614
70202
Q98
E
V
L
A
C
L
N
Q
L
R
Q
T
A
D
I
Frog
Xenopus laevis
Q6INN8
632
72730
S99
A
L
R
L
D
L
L
S
C
L
R
M
L
C
Q
Zebra Danio
Brachydanio rerio
Q502K2
622
71649
D99
E
P
M
K
V
F
N
D
P
I
H
G
H
I
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09374
587
66474
S96
E
H
S
R
F
V
H
S
L
G
T
F
S
L
A
Sea Urchin
Strong. purpuratus
XP_784786
594
68895
D98
L
K
T
K
V
F
N
D
S
I
H
G
H
I
E
Poplar Tree
Populus trichocarpa
XP_002312899
477
54770
L11
Y
S
N
E
E
L
P
L
P
P
V
S
D
F
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_568580
473
54655
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.9
79.5
73.5
N.A.
73.3
65.8
N.A.
N.A.
60
61.8
60.8
N.A.
N.A.
N.A.
22.5
46.8
Protein Similarity:
100
60.2
82.4
83.6
N.A.
83.2
76.2
N.A.
N.A.
74.9
75.3
74.1
N.A.
N.A.
N.A.
40.8
64.2
P-Site Identity:
100
0
86.6
53.3
N.A.
53.3
46.6
N.A.
N.A.
13.3
40
13.3
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
100
0
86.6
80
N.A.
73.3
73.3
N.A.
N.A.
13.3
53.3
26.6
N.A.
N.A.
N.A.
26.6
33.3
Percent
Protein Identity:
28.2
N.A.
N.A.
30.5
N.A.
N.A.
Protein Similarity:
45
N.A.
N.A.
47.2
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
0
0
0
0
8
0
8
% A
% Cys:
0
0
0
0
8
0
0
0
31
0
0
0
0
8
0
% C
% Asp:
0
8
0
0
8
0
0
16
0
0
0
0
8
8
0
% D
% Glu:
39
24
0
8
8
0
0
16
0
0
0
0
0
0
24
% E
% Phe:
0
0
0
0
8
16
0
0
0
0
0
8
0
8
0
% F
% Gly:
24
0
0
0
0
0
0
0
0
8
0
16
0
8
0
% G
% His:
0
8
0
0
0
0
8
0
0
0
16
0
16
0
0
% H
% Ile:
0
0
0
0
0
0
16
0
0
54
0
0
0
16
8
% I
% Lys:
0
8
0
54
39
0
0
0
0
0
0
8
0
0
0
% K
% Leu:
8
8
8
8
0
47
24
8
16
8
0
0
39
8
0
% L
% Met:
0
0
8
0
0
16
0
0
0
0
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
0
24
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
0
0
0
0
8
0
16
8
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
8
8
0
0
47
16
0
0
39
% Q
% Arg:
0
0
47
8
0
0
0
0
0
8
8
16
0
0
0
% R
% Ser:
0
8
8
0
0
0
0
31
8
0
0
8
16
16
8
% S
% Thr:
0
0
8
0
0
0
0
0
0
0
8
8
0
0
0
% T
% Val:
0
8
0
0
16
8
0
0
0
0
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _